GLP-1 receptor agonists (GLP-1 RAs), which regulate glucose metabolism through mechanisms such as enhancing glucose-dependent insulin secretion via the incretin effect, suppressing glucagon secretion, delaying gastric emptying, and supporting pancreatic -cell proliferation, are primarily used in the management of type 2 diabetes mellitus (T2DM) and, in certain cases, obesity [23]
2'-Hydroxycinnamaldehyde alleviates intestinal inflammation by attenuating intestinal mucosal barrier damage via directly inhibiting STAT3
Curr Drug Saf 15:412 Regev A (2014) editor Drug-induced liver injury and drug development: industry perspective
Initial scaffold attempts used simple sponges and hydrogels with moduli (both instantaneous and equilibrium) in the tens of kilopascals (kPa), while the modulus of native cartilage is 2050 times higher
GLP-1 slows gut motility, slowing down digestion and gastric emptying