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These include frequent or prolonged exposure to sunlight, genetic predisposition, and hormonal fluctuations, especially those related to pregnancy or hormonal therapies, all of which can increase melanin production

doi:10.1007/s10557-005-6890-6

NPs play a crucial role in vaccine formulation by acting as both delivery systems and immune-stimulating adjuvants [39]

In mitochondrial muscle disease, however, both muscle and blood showed decreased NAD + levels 15,30 suggesting that blood is a valid source of redox-metabolite analysis in the context of pathology