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Retatrutide's Phase 2a in MASH/MASLD (Sanyal et al., Nat Med 2024) reported approximately 86% relative reduction in liver fat content at 12 mg/week the strongest hepatic-fat data among the incretin class

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This encompasses corticosteroids (triamcinolone, methylprednisolone, betamethasone), local anesthetics (bupivacaine, lidocaine), antispasmodics, and opioids

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