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Impaired detoxification Phase II detoxification pathwaysparticularly sulfation and glucuronidationare quantitatively downregulated during bile acid overload

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Diagnosis-specific IV therapy, such as IV ozone and IV chelation, can be an essential part of a customized treatment plan

doi: 10.3390/nu13113736

In the human kidney, it usually builds up in the segment one section of the proximal tubule, which also causes phosphate reabsorption issues (Fanconi), amino acid, protein, and bicarbonate by damaging transport proteins and mitochondria, which may cause tubular cells to die (4345)