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For NADPH-binding catalases, it has been suggested that enzyme inhibition through the appearance of compound III can be prevented by the NADPH blocking or releasing compound II generation [4, 5, 6]

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Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]

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