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In fact, there are no NICE guidelines relating to Pernicious Anaemia, just a Clinical Knowledge Summary which has a glaring error in it (weve pointed this out to NICE who are considering revising it)

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Its enhanced stability in topical formulations is also relevant for scalp applications where the product must remain active on the skin surface

A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

Before we dive into the particulars of this treatment, its important to understand what exactly this treatment entails