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Collectively, these findings demonstrate that gut microbiota dysbiosis contributes to the pathophysiology of schizophrenia through multifaceted immune-neuro-endocrine pathways, highlighting the MGB axis as a promising target for novel therapeutic strategies

Recycling of oxidized GSH (GSSG) back to its reduced form is facilitated by glutathione reductase (GSR) using NADPH from the pentose phosphate pathway

Deficiencies in other micronutrients, including vitamin B 6 , vitamin B 12 , and omega-3 fatty acids, have been linked to depression, and vitamin D deficiency has also been associated with negative effects on mood (51, 144)

The procedure is done in an outpatient clinic or office setting by trained technicians