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In contrast, excessive or sustained activation of TLRs can promote chronic inflammation and has been implicated in the pathogenesis of numerous immune-mediated disorders (262)

FIGURE 1 3 Mitochondrial quality control Mitochondrial quality control refers to the dynamic and coordinated cycle of regulatory processes that maintain mitochondrial function

In vitro methods are especially favored for their simplicity and cost-effectiveness (Sadeer et al., 2020)

Other infections, such as osteomyelitis of the cervical vertebrae, can also lead to localized pain and require immediate evaluation

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