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Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)

hold a published patent (WO/2023/180570) that covers the in vitro method for identifying anti-senescence compounds based on detecting the binding of said compound in the presence of at least one phosphorylated amino acid in the transcription activation domain (TAD) domain of mammalian protein p53

Wuillemin et al., 1996) and prevented the deposition of C3 and C4 (Wuillemin et al., 1997)

Capsules: Oral capsule discussions are usually compound-specific because digestive stability and absorption can vary widely

There may be some long-term complications with this surgery, such as frequent vomiting, implant malposition, erosion, or weight loss failure