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Users should maintain adequate water intake (30-35ml per kg bodyweight daily), limit alcohol and caffeine in excess depleting body water, and ensure electrolyte balance particularly sodium and potassium regulating cellular hydration supporting optimal peptide response

Long-Term Results : Significant reductions in HbA1c levels may take up to three months of consistent use

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However, given the central role of the thyroid in metabolic regulation, any changes in body weight or metabolism due to semaglutide could theoretically influence thyroid hormone levels or the bodys response to thyroid medication