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Amplifying pathway The efficacy of glutamine in stimulating GLP-1 release cannot be accounted for by its depolarising action only, as asparagine and alanine were less effective as secretagogues even though they induced currents and calcium transients that were, if anything, larger than those produced by glutamine
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A decrease in the levels of TNF--induced IKK/ (inhibitor of nuclear factor kappa-B kinase subunit beta), IB (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), and NF-B (nuclear factor kappa beta cells) was noted
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