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Role of ferroptosis in DACI The regulation of ferroptosis can affect DACI through multiple mechanisms, including the modulation of the GPX4/GSH system, iron and ROS metabolism, mitochondrial homeostasis and the NRF2 and PKR-like endoplasmic reticulum kinase (PERK) signaling pathways (Fig

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If the answer to any of these is yes or uncertain, degraded medication may be contributing to your plateau

False reassurance : Patients may believe they are receiving treatment for their condition when, in reality, the dose is insufficient to provide clinical benefit