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ROS can trigger and maintain the autoimmune cascade by enhancing cell apoptosis and reducing the efficiency of its clearance, and the resulting accumulation of apoptotic residues promotes the formation of auto-antibodies (33)

Activated microglia release pro-inflammatory cytokines, reactive oxygen species, and neurotoxic mediators that exacerbate vascular and white matter injury

However, factors such as aging, stress, poor diet, and environmental toxins can deplete glutathione levels, potentially leading to a range of health issues

The constant production of pro-inflammatory cytokines creates a hostile cellular environment that damages the delicate inner mitochondrial membrane, specifically targeting cardiolipina unique lipid essential for anchoring the electron transport chain complexes

General Chapter Pharmaceutical Compounding, Sterile Preparations