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Since topics may be intrinsically distinguished by other embedded features from the model (e.g., linguistic style, tone) rather than meaningful content, we cluster the cumulative term-frequency inverse-document frequency (c-TF-IDF) representation of these topics using Spectral Clustering to find overarching themes of discussion (groups)

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The study found that more individuals who took semaglutide obtained bodyweight decreases of at least 5% compared to placebo, and more people from the semaglutide group obtained weight losses of 10% or 15%