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Table 18: Treatment Effects for the Primary Endpoints* and their Components* in the DECLARE Trial N=Number of patients, CI=Confidence interval, CV=Cardiovascular, MI=Myocardial infarction, eGFR=estimated glomerular filtration rate, ESRD=End-stage renal disease * Full analysis set

The absence of safety data in these populations should inform clinical decision-making and prescribing practices

The anthelmintic effect of AFA across a broad range of free-living and parasitic nematodes and their in vivo efficacy at treating infected mice make them great candidates for further development as anthelmintics and point to the conclusion that fatty acid metabolism/homeostasis in nematodes is an interesting avenue for future studies of potential anthelmintic targets

But that was only the beginning