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During central sensitization, activation of NMDA receptors results in production of NO which activates neighboring neurons and astrocytes leading to hyperalgesia and allodynia 41,42

This process contributes to maintaining a balance in lipid homeostasis and energy regulation [86, 87]

FDA status CJC-1295 is not FDA-approved for any indication

This occurs as the platelets activate and trigger a temporary surge of inflammation, which is necessary for healing

Brain Behav Immun 25:10251035 Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TK, Brown RH Jr, Carroll MC (2008) T lymphocytes potentiates endogenous neuroprotective inflammation in a mouse model of ALS