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Our answer is rarely stop. Its usually some version of: Stay on the therapeutic dose for at least 3 to 6 months past goal weight to consolidate the loss Step down carefully (if appropriate), watch the scale, and make adjustments as needed Extend the interval for patients maintaining well on any dose, high or low

Acknowledgements This work was supported by the National Natural Science Foundation of China (grant no 81500354), Beijing Municipal Natural Science Foundation (grant no Z13110200400000) and Wu Jieping Medical Foundation (grant no 320.6750.14331)

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Hyperpigmentation is a medical condition, and every treatment described here is prescribed and administered by a licensed provider after an in person evaluation