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Beyond the Scale: What women consistently report loving about tirzepatide goes beyond weight loss

Experts at Obesity Week 2025 emphasized that GLP-1 medications should be viewed much like antihypertensives or diabetes therapieseffective while taken, but not curative once stopped

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33,34 Bone-derived signals, such as osteocalcin (a non-collagenous protein secreted by osteoblasts) and sclerostin (a glycoprotein produced by osteocytes), maintain a bidirectional dialogue with energy metabolism and may influence systemic homeostasis, producing trans-systemic effects during growth

The standard dosing regimen begins with 3 mg once daily for one month, increasing to 7 mg daily, with a possible further increase to 14 mg daily if additional glycaemic control is needed