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If your body senses prolonged calorie deprivation, it can lower your metabolism, making it harder to lose weight

This appetite regulation is one of the first signs that GLP-1 medications are working

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Lifestyle Recommendations for GLP-1 Agonists From a nutritional standpoint, there are three areas of concern related to using GLP-1 agonists: Malnutrition due to decreased food intake Digestive complaints Muscle-wasting GLP-1 agonists can produce a significant reduction in appetite, or they cause some nausea as well

Ive seen this work particularly well for stubborn muscle groups like calves, rear delts, and arms where genetic receptor density and/or fiber type distribution limits growth