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A network meta-analyses put tirzepatide clearly ahead on weight loss, which is the expected outcome for a dual GLP-1/GIP agonist versus a single GLP-1 agonist

They mimick the incretin hormone GLP-1, which stimulates insulin secretion and suppresses appetite

You should speak to your GP first so that your kidney function can be reviewed and any treatment can be prescribed and monitored safely

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Regulatory guidance still recommends stopping the drug if pancreatitis is suspected, but theres no strong evidence of a direct link