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GLP-1 receptor activation in the spinal cord and brainstem may be anti-inflammatory and pain-relieving, while effects on peripheral sensory neurons may, under certain conditions, produce sensitization

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Nat Rev Cancer 4(1):2335 Box NF, Wyeth JR, OGorman LE, Martin NG, Sturm RA (1997) Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair

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