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As previously described the viral infection induced an increase in ROS production directly in CNS cells or indirectly by the infiltrated activated immune system cells, which use ROS release as mechanism to control the infection (Figure 3)

Creissen et al., 1999) as well as the identification of genes encoding the enzymes of glutathione synthesis and reduction in plants (May and Leaver, 1994

While turmeric contains a small percentage of curcumin , modern supplements are formulated to maximize its therapeutic potential

Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis

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