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Hyperoxemia caused by resuscitation with pure oxygen may alter intracellular redox status by increasing oxidized glutathione in asphyxiated newly born infants

10.1016/j.jece.2023.111183

The sterol regulatory element-binding protein (SREBP) family of transcription factors plays a crucial role in lipid metabolism by regulating the expression of a series of enzymes required for lipid synthesis, and nuclear fragments of transcriptionally active SREBPs (nSREBPs) are unstable, degraded by the ubiquitin-proteasome pathway

Subsequently, the therapeutic potential of P-Mn/TI@mHSA was further evaluated by examining the macrophage infiltration within the plaques and assessing plaque vulnerability

References Corben, A