Diseases 12(5):103 Duarte TL, Viveiros N, Godinho C, Duarte D (2024) Heme (dys) homeostasis and liver disease
As with any medication, GLP-1 injections may have side effects, including nausea, vomiting, diarrhea, constipation, and abdominal pain
Retatrutide binds three receptors: the GLP-1 receptor (regulates appetite, insulin secretion, and gastric emptying), the GIP receptor (influences insulin response and adipose handling), and the glucagon receptor (affects energy expenditure and hepatic lipid handling)
Typical weekly range: 0.64.5 mg once weekly (gradual titration over 46 weeks)
Even though they are often viewed as gentler than steroids, using the wrong peptide, dose, or schedule can still disrupt your progress or increase side effects