94 In the colonic mucosa of UC patients, one or more of the three ER stress pathways are activated, resulting in unbalanced protein synthesis and abnormal protein folding, which in turn exacerbates the inflammatory response and intestinal barrier disruption of UC
Observational studies reporting vitamin D and micronutrient insufficiencies during prolonged GLP-1RA use [94, 95, 101] suggest that nutritional monitoring may be warranted, although the magnitude and causal pathways remain to be clarified
Indirect calorimetry Energy expenditure, food intake, respiratory exchange ratio (RER) and locomotor activity were assessed for 96132 h, and after 24 h of acclimatization, in single-housed mice using the Promethion climate-controlled indirect calorimetric system (Sabel Systems)
Modeling energy intake and body weight effects of a long-acting amylin analogue
Mutant neurogenin-3 in congenital malabsorptive diarrhea