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While the evidence is largely based on case reports and physiological rationale rather than large controlled studies, this has led to increased awareness and the development of specific management strategies

These findings exclude the open-chain depsipeptides as cereulide degradation products and further strengthen the proposed release of the target depsipeptide esters by transesterification of biosynthetic intermediates like NRPS-bound PCP- S -esters and TE- O -esters, respectively

doi: 10.5530/jyp.2023.15.59 8

[3] [4] While they produce generalized fat loss, evidence suggests they may have notable effects on abdominal adiposity

Plasma and tissue GSH levels decline with age, while markers of oxidative damage increase, creating a "redox imbalance" implicated in the pathogenesis of age-related diseases [2][3][10][11]