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This year, when she was ready to take a GLP-1 again following a pregnancy, the drug was no longer covered for weight loss

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The clinical observations I describe plateau patterns, side effect profiles, speed of response reflect that vial-based model

The MMRM technique borrows information from participants who are still adhering to the randomized medication to obtain a plausible estimate of what the placebo-adjusted weight loss would have looked like in the hypothetical situation in which all participants were assumed to adhere to the assigned treatment to the same degree as those who were reported to remain adherent throughout the trial