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Recently, it was shown that IL-6-induced autophagy can also contribute to cancer cachexia, a condition characterized by severe loss of body weight and increased muscle wasting and is associated with an increased risk of cancer treatment failure and poor overall survival

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Jun 4 2008;100(11):773-783

Compounds were injected via intraperitoneal administration every day for 3 weeks, and the body weights and tumor volumes were measured every 23 days