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The tripeptide itself functions as a signaling molecule capable of influencing gene expression across hundreds of genes involved in tissue repair and regeneration, extending well beyond simple copper delivery

To address the prevalence of correlational data, this review proposes an evidence grading framework grounded in the pharmacological principles of necessity and sufficiency

doi: 10.1126/science.aaw2622 69 StillmanCMEsteban-CornejoIBrownBBenderCMEricksonKI

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