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The peptide increases survival of enteric neurons, enhances enteric glial cell proliferation, and modulates enteric serotonin release

While the rescued cognitive abilities in GHK-Cu treated 5xFAD mice may be linked to diminished amyloid plaque formation, the extent of associated neurodegeneration in AD progression was not evaluated

Antioxidant properties linked to copper chelation and modulation of cellular oxidative stress

It is particularly relevant for patients with widespread plaques or psoriatic arthritis where systemic immune modulation is desirable