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In the 1970s, Harvard University researcher Joel Habener, with support from the National Institutes of Health, set out to study the hormone glucagon and its role in blood sugar regulation

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He also cautions against use for anyone with severe liver disease or renal failure because these conditions may slow the elimination of PT-141 from the body

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It works primarily as a gel-forming bulk fiber: when it absorbs water, it expands and creates a gel that adds volume and softness to stool