Further experimental investigations are needed to determine whether the beneficial effects of any small molecules that stimulate or inhibit erythrocyte apoptosis are effective in the ex vivo or in vivo treatment of anemia, malaria, or systemic pathologies associated with eryptosis [211]
Association between dietary flavonol intake and mortality risk in the U.S
After treatment, cells were labeled with Annexin V/Propidium Iodide (#640914, Biolegend, USA) for 15 min in the dark ( n = 3)
EZH2: Enhancer of zeste homolog 2, JNK: Jun N-terminal kinase, H3K4me3: Trimethylated H3 lysine 4, CU17: curcumin derivative, SIRT1: Sirtuin 1, HDAC1,3: histone deacetylase, H2A.X: histone family member X, HDAC: histone deacetylases
Prolonged treatment of hypertension with a thiazide diuretic, however, was associated with a more significant incidence of neovascular AMD, possibly due to the known phototoxic effects of thiazide diuretics (De la Marnierre 2003)
