doi: 10.3390/ijms23052717 Summary Keywords peripheral serotonin, L-carnitine, fatigue, hypothyroidism, chronic fatigue syndrome (CFS), myalgic encephalomyelitis (ME), systemic exertion intolerance disease (SEID), mitochondria Citation Raij T and Raij K (2024) Association between fatigue, peripheral serotonin, and L-carnitine in hypothyroidism and in chronic fatigue syndrome
assists in hundreds of enzymatic reactions involved in the synthesis of energy, DNA, and proteins
The enrolled patients suffered from peripheral mono- and polyneuropathies of various origins including entrapment, traumatic, toxic/alcoholic, diabetic, metabolic, idiopathic, vascular or infective aetiology
Renal reabsorption is efficient at low plasma concentrations but becomes saturated at higher levels, leading to increased clearance