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J147, a curcumin-derived compound, targets mitochondrial ATP synthase (ATP5A)

The injection of a DNA vaccine expressing xCT proteins and immune targeting of xCT antigens on the cell surface effectively inhibited subcutaneous tumor growth and lung metastasis in mice and increased the chemosensitivity of breast CSCs to doxorubicin (44,83,92)

Seven of the 11 patients in the combined therapy group completed the full year of follow-up data

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