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Notably, the growth rates demonstrated a high linear correlation with enzyme activities determined via recombinant protein assays

Between Fc5 and -hairpin 2, Q81 J can form a hydrogen bond with the carbonyl group of F358 C3-5B , and several interactions occur between residues T84-Q87 on J chain and N545-R550 on C4-5B including a van der Waals contact between A85 J to V547 C4-5B (Fig

De novo synthesis of GSH is controlled by the nuclear factor erythroid 2-related factor 2 (Nrf2), as it is a major regulator of oxidative stress signaling [37,38]