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The investigators provided evidence that CRP is not merely a marker of inflammation, but instead has a causal role in the development of obesity ( As part of the CORDIOPREV (CORonary Diet Intervention with Olive oil and cardiovascular PREVention) prospective RCT, researchers suggest that the genetic variant of the NLRP3 inflammasome may modulate the benefits of the MedDiet (79)

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Unlike systemic immunotherapies that are limited by toxicity and off-target effects, injectable or implantable hydrogels can provide localized, sustained, and precisely dosed delivery of immune modulators [61]

Yeo Y.H., Rezaie A., Hsieh T.Y., Hu X