Key takeaways Late periods can be influenced by a variety of factors including contraceptives, perimenopause, weight changes, and hormonal imbalances, each affecting the bodys menstrual cycle in different ways
Agustinho DP, Miller LC, Li LX, Doering TL
One pen contains 100 units, each at 10 micrograms
Signs that you may be ready to increase your dose Your provider will typically consider a dose increase when: You have been on your current dose for at least 4 weeks with no significant side effects Nausea, vomiting, or stomach discomfort from the previous dose increase has resolved Your weight loss has plateaued at the current dose, and you have not yet reached your goal Your blood sugar levels (if you have diabetes) are not yet in your target range Signs you are not ready to increase Your provider will typically delay a dose increase if: You are still experiencing nausea, vomiting, diarrhea, or stomach pain from your current dose You have missed doses recently due to side effects You have experienced any serious adverse event at the current dose that has not fully resolved Do you need to reach 15 mg
To ensure the comprehensiveness of the analysis, we conducted a literature search in the Web of Science, Scopus, and PubMed databases, with the search scope ending in the end of 2025