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And while it is progress, the actual number was lowering risk from 8% in the placebo group to 6.5% in the treatment group or only 1.5% absolute risk reduction

Some practitioners hold patients at 10 mg if weight loss trajectory is satisfactory, reserving higher doses for plateaus

The lower starting dose was specifically chosen based on phase 3 trial refinements to improve gastrointestinal tolerability compared to earlier, more rapid dose escalation schemes

Individuals with cardiovascular disease or significant cardiovascular risk factors should generally favor Mounjaro pending cardiovascular outcome trial data for Retatrutide

Unger, visionary endocrinologist and preeminent authority on diabetes', Center Times Plus