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GHR is a 638 amino acid long homodimeric receptor with one cytokine receptor homology domain (CRH), a single-pass transmembrane domain, and cytoplasmic intracellular domain (ICD) (Figure 1)
Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung
Firstly, SLC7A11 expression in PTC cells was estimated
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology
Loss of intracellular GSH is likely multifactorial and includes generation of high levels of hydroperoxy-phospholipids (which directly or indirectly oxidize GSH and limit GSSG recycling by reductases) as well as active export of GSSG generated by high GPX4 activity (7, 8, 21)
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