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doi: 10.1371/journal.pone.0225392 59 ShinoharaM.KanekiyoT.TachibanaM.KurtiA.ShinoharaM.FuY.et al

Nutr Res Rev 22(1):4967 Dos Santos TM, Jnior OVR, Alves VS, Coutinho-Silva R, Savio LEB, Wyse AT (2021) Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents

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The same case report documented biological age reduction and telomere length increase, with the patient's biological age decreasing by 7.9 years (from 75.93 to 68.03) and telomere length increasing from 6.45 to 6.59 kb over one year of treatment