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GLP-1 is a naturally occurring incretin hormone released by the intestine in response to food intake

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Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

Avoid using the medication if you have a history of medullary thyroid carcinoma, pancreatitis, severe gastrointestinal disorders, or multiple endocrine neoplasia type 2 (MEN2) syndrome

Although compounded GLP-1s are produced in facilities that are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality