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Semaglutide, tirzepatide, liraglutide: You might have heard of these type 2 diabetes medications known as GLP-1 drugs

Kaballo, M

Originally developed for treatment of type 2 diabetes in 2004, and later approved for weight loss in 2014, GLP-1s have demonstrated clinically meaningful reductions in A1c as well as unprecedented weight loss, with patients losing up to 20% of t heir body weight. There has been rapid adoption and a surge in demand for incretin-based therapies

Participants waist circumference didnt change much between years one and two

In the mid-stage trial, patients who received liraglutide most commonly experienced gastrointestinal side effects associated with other GLP-1s, such as nausea