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Such a setup would precisely delineate the NSC-derived paracrine factors (e.g., BDNF, VEGF [18, 32], TGF-) responsible for suppressing microglial activation and promoting an anti-inflammatory phenotype, independently of in vivo complexities

Comorbidities collected within 6 months before the index date included metabolic syndrome (hypertension and dyslipidemia), cardiovascular disorders (heart failure, myocardial infarction, ischemic stroke, peripheral arterial disease, coronary artery disease, cardiovascular disease [CVD]), and chronic kidney disease

Yale is a Wilson Disease Center of Excellence

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Yes, SYS is a GMP-certified manufacturer