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Even though it is inexpensive, we do not recommend cyano B12 to anyone because the body must use a methylation reaction to cleave its cyanide molecule, which is a demanding process

A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

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Due to patient selection of only male Caucasian veterans, the extension of the study result to the general population can be limited