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The evidence base includes the STEP program for semaglutide (NEJM, 2021) and the SURMOUNT program for tirzepatide (NEJM, 2022), with SURMOUNT-OSA extending tirzepatide study into obstructive sleep apnea (NEJM, 2024)
NADs that target proteins Aptamers are single-stranded oligonucleotide molecules that have specific recognition functions obtained via iterative screening from large libraries of random oligonucleotides using the systematic evolution of ligands by exponential enrichment (SELEX) technology
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doi: 10.1073/pnas.1508740112 77 MarkleJGFrankDNAdeliKvon BergenMDanskaJS
Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: an adjusted indirect treatment comparison
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