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While reactive oxygen species such as superoxide are a normal byproduct of energy production in mitochondria, superoxide radicals generated by glucose overload may cause diabetic complications (Giacco 2010

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Leydig cells in the testes are responsible for testosterone production, and their senescence contributes to the age-related decline in testosterone levels (Zhang et al., 2020)

Gutman highlights that oral glutathione is largely broken down in the digestive tract due to the action of specific enzymes

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