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Chronic elevation of cortisol levels , as seen in Cushing's syndrome, is associated with multiple adverse effects including: Central obesity and metabolic syndrome Insulin resistance and type 2 diabetes Hypertension and cardiovascular disease Osteoporosis and increased fracture risk Mood disturbances, anxiety, and depression Impaired immune function and wound healing Psychological stress can affect cortisol patterns, though the relationship is complex and varies between individuals

Its not just about having a TSH in the lab reference range

To prevent this, pinch the skin to lift the fatty layer before injecting at a 90-degree angle

Obesity (2015) 23(6):111929

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