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SIRT1 is also known as the longevity gene because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer

MOTS-c is the most studied of these peptides

For enhanced results, some patients find that consuming a small amount of caffeine alongside these medications helps increase the absorption rate and provides additional vasoconstriction

References Alisi A, Piemonte F, Pastore A, Panera N, Passarelli C, Tozzi G, Petrini S, Pietrobattista A, Bottazzo GF, Nobili V (2009) Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants

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