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and d represents the number of reports with neither target drug exposure nor target AEs

In healthy fasted individuals, it is recognized that peripheral plasmatic active GLP-1 (7-36) NH2 plasmatic levels hover around 5 pM, but within 510 min after an oral glucose load, they start to rise, up to a maximum of less than 10 pM after 4090 min, and slowly descend back to baseline values in 150 min

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We hypothesized that the increase in endogenous GLP-1 levels induced by lipid nanocapsules could reach therapeutic levels in the context of MASLD

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