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In this regard, good results have been reached through photodynamic therapy, which is based on the generation of ROS after stimulation of a photosensitizer by light: cancer cells under treatment internalize porphyrin precursor molecules to induce the formation of ROS that lead to photooxidative stress and cancer-specific cell death 164,165

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7 Conclusion This review summarizes the latest advances in drug resistance mechanisms and the clinical translation of High-Grade Serous Ovarian Carcinoma (HGSOC)